Gulisa Turashvili

Assistant Professor at University of Toronto

Dr. Turashvili obtained her MD degree at Tbilisi State Medical University (Georgia) and PhD degree (Pathology) at Palacky University (Czech Republic). After several years of research at University of British Columbia under Dr. Aparicio from 2009 to 2011 (Vancouver, BC), she completed residency training in Anatomical Pathology at Queen`s University (Kingston, ON), and two years of fellowship training in Breast and Gynecologic Pathology at Memorial Sloan Kettering Cancer Center (New York, NY). Dr. Turashvili joined the staff of Mount Sinai Hospital and the faculty of the University of Toronto in 2018.

Papers

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.

In vivo radioimaging of bradykinin receptor b1, a widely overexpressed molecule in human cancer.

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells.

The landscape of cancer genes and mutational processes in breast cancer.

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer.

PPM1H is a p27 phosphatase implicated in trastuzumab resistance.

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.

JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data.

Mll5 is required for normal spermatogenesis.

Nucleic acid quantity and quality from paraffin blocks: defining optimal fixation, processing and DNA/RNA extraction techniques.

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent.

ARID1A mutations in endometriosis-associated ovarian carcinomas.

P-cadherin expression as a prognostic biomarker in a 3992 case tissue microarray series of breast cancer.

Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy.

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis.

A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability.

Columnar cell lesions, mammographic density and breast cancer risk.

Are columnar cell lesions the earliest histologically detectable non-obligate precursor of breast cancer?